VSIG4 Antibody

Product Specifications

Background

This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq].

NCBI Gene ID

11326

Swiss Prot

Q9Y279

Accession Number

Q9Y279

Host

Rabbit

Reactivity

Human

Immunogen

This VSIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of human VSIG4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

44 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

VSIG4

NCBI Official Name

V-set and immunoglobulin domain-containing protein 4

NCBI Organism

Homo sapiens

Background Reference 01

Guo, S., et al. Clin. Immunol. 136 (2) :282-291 (2010)

Background Reference 02

Van Loo, P., et al. Haematologica 95 (3) :440-448 (2010)

Background Reference 03

Xu, S., et al. Immunol. Lett. 128 (1) :46-50 (2010)

Background Reference 04

He, J.Q., et al. Mol. Immunol. 45 (16) :4041-4047 (2008)

Other Product Names

V-set and immunoglobulin domain-containing protein 4, Protein Z39Ig, VSIG4, CRIg, Z39IG

Tested Applications

Protein ID

59799152

Physical Properties

Liquid

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