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SCRIB Antibody

Product Specifications

Background

SCRIB is a cytoplasmic multimodular scaffold protein targeted to epithelial adherens junctions and neuronal presynaptic compartments. SCRIB and its orthologs in vertebrates and invertebrates participate in cell polarization (summary by Nola et al., 2008 [PubMed 18716323]) .

NCBI Gene ID

23513

Swiss Prot

Q14160

Accession Number

Q14160

Host

Rabbit

Reactivity

Human

Immunogen

This SCRIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-410 amino acids from the N-terminal region of human SCRIB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

175 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SCRIB

NCBI Official Name

Protein scribble homolog

NCBI Organism

Homo sapiens

Background Reference 01

Liu, H., et al. J. Virol. 84 (21) :11164-11174 (2010)

Background Reference 02

Nagasaka, K., et al. Oncogene 29 (38) :5311-5321 (2010)

Background Reference 03

Ivanov, A.I., et al. Am. J. Pathol. 176 (1) :134-145 (2010)

Background Reference 04

Ouyang, Z., et al. Oncol. Res. 18 (11-12), 593-599 (2010) :

Other Product Names

Protein scribble homolog, Scribble, hScrib, Protein LAP4, SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL

Tested Applications

WB

Protein ID

261260101

Physical Properties

Liquid

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