CLEC6A Antibody

Product Specifications

Background

Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 [PubMed 15175046]) .

NCBI Gene ID

93978

Swiss Prot

Q6EIG7

Accession Number

Q6EIG7

Host

Rabbit

Reactivity

Human

Immunogen

This CLEC6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-163 amino acids from the C-terminal region of human CLEC6A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CLEC6A

NCBI Official Name

C-type lectin domain family 6 member A

NCBI Organism

Homo sapiens

Background Reference 01

Gavino, A.C., et al. Exp. Dermatol. 14 (4) :281-288 (2005)

Background Reference 02

Flornes, L.M., et al. Immunogenetics 56 (7) :506-517 (2004)

Background Reference 03

Kanazawa, N., et al. J. Invest. Dermatol. 122 (6) :1522-1524 (2004)

Other Product Names

C-type lectin domain family 6 member A, C-type lectin superfamily member 10, Dendritic cell-associated C-type lectin 2, DC-associated C-type lectin 2, Dectin-2, CLEC6A, CLECSF10, DECTIN2