HAS3 Antibody

Product Specifications

Background

The protein encoded by this gene is involved in the synthesis of the unbranched glycosaminoglycan hyaluronan, or hyaluronic acid, which is a major constituent of the extracellular matrix. This gene is a member of the NODC/HAS gene family. Compared to the proteins encoded by other members of this gene family, this protein appears to be more of a regulator of hyaluronan synthesis. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

3038

Swiss Prot

O00219

Accession Number

O00219

Host

Rabbit

Reactivity

Human

Immunogen

This HAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the Central region of human HAS3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

HAS3

NCBI Official Name

Hyaluronan synthase 3

NCBI Organism

Homo sapiens

Background Reference 01

Dunn, K.M., et al. Surgery 145 (3) :322-329 (2009)

Background Reference 02

Nykopp, T.K., et al. BMC Cancer 9, 143 (2009) :

Background Reference 03

Nair, S., et al. J. Nephrol. 21 (3) :400-405 (2008)

Background Reference 04

Campo, G.M., et al. Mol. Cell. Biochem. 292 (1-2), 169-178 (2006) :

Other Product Names

Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3, HAS3

Tested Applications

Physical Properties

Liquid

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