KRT33B Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B. [provided by RefSeq].

NCBI Gene ID

3884

Swiss Prot

Q14525

Accession Number

Q14525

Host

Rabbit

Reactivity

Human

Immunogen

This KRT33B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-91 amino acids from the N-terminal region of human KRT33B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KRT33B

NCBI Official Name

Keratin, type I cuticular Ha3-II

NCBI Organism

Homo sapiens

Background Reference 01

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 02

Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)

Background Reference 03

Anderson, N.L., et al. Mol. Cell Proteomics 3 (4) :311-326 (2004)

Background Reference 04

Langbein, L., et al. J. Biol. Chem. 274 (28) :19874-19884 (1999)

Other Product Names

Keratin, type I cuticular Ha3-II, Hair keratin, type I Ha3-II, Keratin-33B, K33B, KRT33B, HHA3-II, HKA3B, KRTHA3B

Tested Applications

Protein ID

6686299

Physical Properties

Liquid

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