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MTHFS Antibody

Product Specifications

Background

MTHFS contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.

NCBI Gene ID

10052802110588

Swiss Prot

P49914

Accession Number

P49914

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MTHFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human MTHFS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MTHFS

NCBI Official Name

5-formyltetrahydrofolate cyclo-ligase

NCBI Organism

Homo sapiens

Background Reference 01

Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19 (7) :1822-1830 (2010)

Background Reference 02

Hazra, A., et al. Cancer Causes Control 21 (3) :331-345 (2010)

Background Reference 03

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 04

Wu, D., et al. Cancer Res. 69 (18) :7294-7301 (2009)

Other Product Names

5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydrofolate synthetase, MTHFS, Methenyl-THF synthetase, MTHFS

Tested Applications

WB

Physical Properties

Liquid

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