EXTL1 Antibody

Product Specifications

Background

This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin.

NCBI Gene ID

2134

Swiss Prot

Q92935

Accession Number

Q92935

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This EXTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-676 amino acids from the C-terminal region of human EXTL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

75 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

EXTL1

NCBI Official Name

Exostosin-like 1

NCBI Organism

Homo sapiens

Background Reference 01

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 02

Mathysen, D., et al. Eur. J. Cancer 40 (8) :1255-1261 (2004)

Background Reference 03

Zak, B.M., et al. Biochim. Biophys. Acta 1573 (3) :346-355 (2002)

Background Reference 04

Kim, B.T., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (13) :7176-7181 (2001)

Other Product Names

Exostosin-like 1, Exostosin-L, Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostosis-like protein, EXTL1, EXTL