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ABCC9 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. No disease has been associated with this gene thus far. Alternative splicing of this gene results in several products, two of which result from differential usage of two terminal exons and one of which results from exon deletion.

NCBI Gene ID

10060

Swiss Prot

O60706

Accession Number

O60706

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ABCC9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-669 amino acids from the Central region of human ABCC9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

174 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ABCC9

NCBI Official Name

ATP-binding cassette sub-family C member 9

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Zimmerman, R.S., et al. Genet. Med. 12 (5) :268-278 (2010)

Background Reference 03

Ellis, J.A., et al. Physiol. Genomics 40 (3) :184-188 (2010)

Background Reference 04

Kim, S.J., et al. Biochem. Biophys. Res. Commun. 391 (1) :974-978 (2010)

Other Product Names

ATP-binding cassette sub-family C member 9, Sulfonylurea receptor 2, ABCC9, SUR2

Tested Applications

WB

Physical Properties

Liquid

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