ADNP Antibody

Product Specifications

Background

Vasoactive intestinal peptide is a neuroprotective factor that has a stimulatory effect on the growth of some tumor cells and an inhibitory effect on others. This gene encodes a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. This gene is also upregulated in normal proliferative tissues. Finally, the encoded protein may increase the viability of certain cell types through modulation of p53 activity. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].

NCBI Gene ID

23394

Swiss Prot

Q9H2P0

Accession Number

Q9H2P0

Host

Rabbit

Reactivity

Human

Immunogen

This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ADNP

NCBI Official Name

Activity-dependent neuroprotector homeobox protein

NCBI Organism

Homo sapiens

Background Reference 01

Braitch, M., et al. Neuroimmunomodulation 17 (2) :120-125 (2010)

Background Reference 02

Mandel, S., et al. J. Biol. Chem. 282 (47) :34448-34456 (2007)

Background Reference 03

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 04

Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)

Other Product Names

Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein, ADNP, ADNP1, KIAA0784

Tested Applications

Protein ID

24636245

Physical Properties

Liquid

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