ID3 Antibody

Product Specifications

Background

Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.

NCBI Gene ID

3399

Swiss Prot

Q02535

Accession Number

Q02535

Host

Rabbit

Reactivity

Human

Immunogen

This ID3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the C-terminal region of human ID3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

13 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ID3

NCBI Official Name

DNA-binding protein inhibitor ID-3

NCBI Organism

Homo sapiens

Background Reference 01

Shuno, Y., et al. J. Surg. Res. 161 (1) :76-82 (2010)

Background Reference 02

Doran, A.C., et al. Circ. Res. 106 (7) :1303-1311 (2010)

Background Reference 03

McGeachie, M., et al. Circulation 120 (24) :2448-2454 (2009)

Background Reference 04

Higgins, S., et al. Endocrinology 150 (9) :4044-4055 (2009)

Other Product Names

DNA-binding protein inhibitor ID-3, Class B basic helix-loop-helix protein 25, bHLHb25, Helix-loop-helix protein HEIR-1, ID-like protein inhibitor HLH 1R21, Inhibitor of DNA binding 3, Inhibitor of differentiation 3, ID3, 1R21, BHLHB25, HEIR1