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TIPRL Antibody

Product Specifications

Background

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]) .

NCBI Gene ID

261726

Swiss Prot

O75663

Accession Number

O75663

Host

Rabbit

Reactivity

Human

Immunogen

This TIPRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-218 amino acids from the C-terminal region of human TIPRL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TIPRL

NCBI Official Name

TIP41-like protein

NCBI Organism

Homo sapiens

Background Reference 01

Ehret, G.B., et al. Eur. J. Hum. Genet. 17 (12) :1650-1657 (2009)

Background Reference 02

Cheung, C.L., et al. Hum. Mol. Genet. 18 (4) :679-687 (2009)

Background Reference 03

Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)

Background Reference 04

McConnell, J.L., et al. Oncogene 26 (41) :6021-6030 (2007)

Other Product Names

TIP41-like protein, Putative MAPK-activating protein PM10, Type 2A-interacting protein, TIP, TIPRL

Tested Applications

WB

Physical Properties

Liquid

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