GP9 Antibody
Product Specifications
Background
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq].
NCBI Gene ID
2815
Swiss Prot
P14770
Accession Number
P14770
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This GP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the C-terminal region of human GP9.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GP9
NCBI Official Name
Platelet glycoprotein IX
NCBI Organism
Homo sapiens
Background Reference 01
Munday, A.D., et al. J. Thromb. Haemost. 8 (1) :163-172 (2010)
Background Reference 02
Mo, X., et al. J. Thromb. Haemost. 7 (9) :1533-1540 (2009)
Background Reference 03
Mangin, P.H., et al. J. Thromb. Haemost. 7 (9) :1550-1555 (2009)
Background Reference 04
Strassel, C., et al. Haematologica 94 (6) :800-810 (2009)
Other Product Names
Platelet glycoprotein IX, GP-IX, GPIX, Glycoprotein 9, CD42a, GP9
Tested Applications
WB
Protein ID
2822110
Physical Properties
Liquid
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