SRGAP1 Antibody

Product Specifications

Background

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

NCBI Gene ID

57522

Swiss Prot

Q7Z6B7

Accession Number

Q7Z6B7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SRGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-497 amino acids from the Central region of human SRGAP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

124 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SRGAP1

NCBI Official Name

SLIT-ROBO Rho GTPase-activating protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 02

Voss, M., et al. BMC Immunol. 10, 53 (2009) :

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

SLIT-ROBO Rho GTPase-activating protein 1, srGAP1, Rho GTPase-activating protein 13, SRGAP1, ARHGAP13, KIAA1304

Tested Applications

Protein ID

48428624

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RR216134 10 µg

Nipsnap3a (NM_001161846) Rat Tagged ORF Clone

Ask

View Details

bsm-52292R-Cy5-01 20 µL

MMP12 Recombinant Antibody, Cy5 Conjugated

Ask

View Details

bsm-52292R-Cy5-02 100 µL

MMP12 Recombinant Antibody, Cy5 Conjugated

Ask

View Details

sc-251147 1 g

Tetraammineplatinum (II) chloride

Ask

View Details

46991034 100 µg

TMEM205 Protein Lysate (Mouse) with C-HA Tag

Ask

View Details