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CBR4 Antibody

Product Specifications

Background

The heteroteramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity. May play a role in biosynthesis of fatty acids in mitochondria. The homotetramer may act as NADPH-dependent quinone reductase. Has broad substrate specificity and reduces 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro) .

NCBI Gene ID

84869

Swiss Prot

Q8N4T8

Accession Number

Q8N4T8

Host

Rabbit

Reactivity

Human

Immunogen

This CBR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the C-terminal region of human CBR4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CBR4

NCBI Official Name

Carbonyl reductase family member 4

NCBI Organism

Homo sapiens

Background Reference 01

Chen, Z., et al. FASEB J. 23 (11) :3682-3691 (2009)

Background Reference 02

Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :

Background Reference 03

Endo, S., et al. Biochem. Biophys. Res. Commun. 377 (4) :1326-1330 (2008)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Carbonyl reductase family member 4, 1---, 3-oxoacyl-[acyl-carrier-protein] reductase, 111-, Quinone reductase CBR4, CBR4

Tested Applications

WB

Protein ID

269849708

Physical Properties

Liquid

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