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QPCT Antibody

Product Specifications

Background

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.

NCBI Gene ID

25797

Swiss Prot

Q16769

Accession Number

Q16769

Host

Rabbit

Reactivity

Human

Immunogen

This QPCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-343 amino acids from the C-terminal region of human QPCT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-199

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

QPCT

NCBI Official Name

Glutaminyl-peptide cyclotransferase

NCBI Organism

Homo sapiens

Background Reference 01

Morawski, M., et al. Acta Neuropathol. 120 (2) :195-207 (2010)

Background Reference 02

Stephan, A., et al. FEBS J. 276 (22) :6522-6536 (2009)

Background Reference 03

Marroni, F., et al. Circ Cardiovasc Genet 2 (4) :322-328 (2009)

Background Reference 04

Calvaresi, M., et al. Proteins 73 (3) :527-538 (2008)

Other Product Names

Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, sQC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC, QPCT

Tested Applications

WB

Protein ID

2498824

Physical Properties

Liquid

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