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COL4A6 Antibody

Product Specifications

Background

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

NCBI Gene ID

1288

Swiss Prot

Q14031

Accession Number

Q14031

Host

Rabbit

Reactivity

Human

Immunogen

This COL4A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-859 amino acids from the Central region of human COL4A6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=59-095

Calculated Molecular Weight

164 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

COL4A6

NCBI Official Name

Collagen alpha-6 (IV) chain

NCBI Organism

Homo sapiens

Background Reference 01

Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :

Background Reference 02

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 03

Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :

Background Reference 04

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Other Product Names

Collagen alpha-6 (IV) chain, COL4A6

Tested Applications

WB

Protein ID

116241307

Physical Properties

Liquid

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