REXO2 Antibody

Product Specifications

Background

Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mononucleotides in a sequential manner.

NCBI Gene ID

25996

Swiss Prot

Q9Y3B8

Accession Number

Q9Y3B8

Host

Rabbit

Reactivity

Human

Immunogen

This REXO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-157 amino acids from the Central region of human REXO2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

REXO2

NCBI Official Name

Oligoribonuclease, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Young Park, A., et al. Protein Expr. Purif. 57 (2) :180-187 (2008)

Background Reference 02

Rush, J., et al. Nat. Biotechnol. 23 (1) :94-101 (2005)

Background Reference 03

Ito, S., et al. Photochem. Photobiol. 80 (2) :281-285 (2004)

Background Reference 04

Simpson, J.C., et al. EMBO Rep. 1 (3) :287-292 (2000)

Other Product Names

Oligoribonuclease, mitochondrial, 31--, RNA exonuclease 2 homolog, Small fragment nuclease, REXO2, SFN, SMFN

Tested Applications

Protein ID

116242694

Physical Properties

Liquid

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