ARAP2 Antibody

Product Specifications

Background

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5) -trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.

NCBI Gene ID

116984

Swiss Prot

Q8WZ64

Accession Number

Q8WZ64

Host

Rabbit

Reactivity

Human

Immunogen

This ARAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human ARAP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

193 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ARAP2

NCBI Official Name

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Gavicherla, B., et al. Infect. Immun. 78 (11) :4532-4541 (2010)

Background Reference 02

Liu, C., et al. Mol. Med. 14 (9-10), 575-581 (2008) :

Background Reference 03

Yoon, H.Y., et al. J. Cell. Sci. 119 (PT 22), 4650-4666 (2006) :

Background Reference 04

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1, Protein PARX, ARAP2, CENTD1, KIAA0580

Tested Applications

Protein ID

308153629

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS9360896-01 48 Well

Sheep Alveolar Type I Cell 56kDa Protein (TI56) ELISA Kit

Ask

View Details

MBS9360896-02 96 Well

Sheep Alveolar Type I Cell 56kDa Protein (TI56) ELISA Kit

Ask

View Details

MBS9360896-03 5x 96 Well

Sheep Alveolar Type I Cell 56kDa Protein (TI56) ELISA Kit

Ask

View Details

MBS9360896-04 10x 96 Well

Sheep Alveolar Type I Cell 56kDa Protein (TI56) ELISA Kit

Ask

View Details

A22647-25 25 mg

Methoxy-PMS 25mg

Ask

View Details

ABP55135-01 30 µL

Olfactory receptor 5H15 Polyclonal Antibody

Ask

View Details