TTC8 Antibody

Product Specifications

Background

This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.

NCBI Gene ID

123016

Swiss Prot

Q8TAM2

Accession Number

Q8TAM2

Host

Rabbit

Reactivity

Human

Immunogen

This TTC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human TTC8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TTC8

NCBI Official Name

Tetratricopeptide repeat protein 8

NCBI Organism

Homo sapiens

Background Reference 01

Riazuddin, S.A., et al. Am. J. Hum. Genet. 86 (5) :805-812 (2010)

Background Reference 02

Bin, J., et al. Hum. Mutat. 30 (7), E737-E746 (2009) :

Background Reference 03

Chung, W.K., et al. Hum. Hered. 67 (3) :193-205 (2009)

Background Reference 04

Nachury, M.V., et al. Cell 129 (6) :1201-1213 (2007)

Other Product Names

Tetratricopeptide repeat protein 8, TPR repeat protein 8, Bardet-Biedl syndrome 8 protein, TTC8, BBS8

Tested Applications

Protein ID

308153511

Physical Properties

Liquid

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