PLEKHF2 Antibody

Product Specifications

Background

PLEKHF2 (Phafin 2) is a PH and FYVE domain containing protein 2. The FYVE domain and Zinc binding domain targets proteins to membrane lipids via interaction with phosphatidylinositol 3 phosphate, PI3P. The FYVE domain and Zinc binding domain present in Fab1, YOTB, Vac1, and EEA1.

NCBI Gene ID

79666

Swiss Prot

Q9H8W4

Accession Number

Q9H8W4

Host

Rabbit

Reactivity

Human

Immunogen

This PLEKHF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the Central region of human PLEKHF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PLEKHF2

NCBI Official Name

Pleckstrin homology domain-containing family F member 2

NCBI Organism

Homo sapiens

Background Reference 01

Lin, W.J., et al. Biochem. Biophys. Res. Commun. 391 (1) :1043-1048 (2010)

Background Reference 02

Li, C., et al. J. Mol. Med. 86 (4) :471-484 (2008)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Other Product Names

Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2, Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains, EAPF, PH and FYVE domain-containing protein 2, Phafin-2, Phafin2, Zinc finger FYVE domain-containing protein 18, PLEKHF2, ZFYVE18