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CCRL2 Antibody

Product Specifications

Background

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.

NCBI Gene ID

9034

Swiss Prot

O00421

Accession Number

O00421

Host

Rabbit

Reactivity

Human

Immunogen

This CCRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human CCRL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CCRL2

NCBI Official Name

C-C chemokine receptor-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)

Background Reference 02

Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

Background Reference 03

Leick, M., et al. Immunology 129 (4) :536-546 (2010)

Background Reference 04

Segat, L., et al. Vaccine 28 (10) :2201-2206 (2010)

Other Product Names

C-C chemokine receptor-like 2, Chemokine receptor CCR11, Chemokine receptor X, Putative MCP-1 chemokine receptor, CCRL2, CCR11, CCR6, CKRX, CRAM, HCR

Tested Applications

WB

Physical Properties

Liquid

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