Mouse Bmpr1a Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

NCBI Gene ID

12166

Swiss Prot

P36895

Accession Number

P36895

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Bmpr1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-197 amino acids from the Central region of mouse Bmpr1a.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

60 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Bmpr1a

NCBI Official Name

Bone morphogenetic protein receptor type-1A

NCBI Organism

Mus musculus

Background Reference 01

Drogat, B., et al. Blood 116 (12) :2141-2151 (2010)

Background Reference 02

Leung, A.W., et al. Dev. Dyn. 239 (9) :2319-2329 (2010)

Background Reference 03

Mira, H., et al. Cell Stem Cell 7 (1) :78-89 (2010)

Background Reference 04

Libusova, L., et al. Development 137 (14) :2297-2305 (2010)

Other Product Names

Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, SKR5, CD292, Bmpr1a, Acvrlk3, Bmpr