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CD226 Antibody

Product Specifications

Background

CD226 is a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq].

NCBI Gene ID

10666

Swiss Prot

Q15762

Accession Number

Q15762

Host

Rabbit

Reactivity

Human

Immunogen

This CD226 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-335 amino acids from the C-terminal region of human CD226.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CD226

NCBI Official Name

CD226 antigen

NCBI Organism

Homo sapiens

Background Reference 01

Lofgren, S.E., et al. Arthritis Rheum. 62 (11) :3404-3414 (2010)

Background Reference 02

Carlsten, M., et al. Leukemia 24 (9) :1607-1616 (2010)

Background Reference 03

Plant, D., et al. Ann. Rheum. Dis. 69 (8) :1548-1553 (2010)

Background Reference 04

Alcina, A., et al. Genes Immun. 11 (5) :439-445 (2010)

Other Product Names

CD226 antigen, DNAX accessory molecule 1, DNAM-1, CD226, CD226, DNAM1

Tested Applications

WB

Protein ID

317373338

Physical Properties

Liquid

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