TP53BP2 Antibody

Product Specifications

Background

TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

7159

Swiss Prot

Q13625

Accession Number

Q13625

Host

Rabbit

Reactivity

Human

Immunogen

This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

126 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

TP53BP2

NCBI Official Name

Apoptosis-stimulating of p53 protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In press :

Background Reference 02

Zhao, J., et al. Hepatology 51 (1) :142-153 (2010)

Background Reference 03

Hirata, H., et al. J. Urol. 182 (2) :721-727 (2009)

Background Reference 04

Kweekel, D.M., et al. Br. J. Cancer 101 (2) :357-362 (2009)

Other Product Names

Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP