EME2 Antibody
Product Specifications
Background
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760) -type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]) .
NCBI Gene ID
197342
Swiss Prot
A4GXA9
Accession Number
A4GXA9
Host
Rabbit
Reactivity
Human
Immunogen
This EME2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-278 amino acids from the C-terminal region of human EME2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EME2
NCBI Official Name
Probable crossover junction endonuclease EME2
NCBI Organism
Homo sapiens
Background Reference 01
Ciccia, A., et al. Mol. Cell 25 (3) :331-343 (2007)
Background Reference 02
Ciccia, A., et al. J. Biol. Chem. 278 (27) :25172-25178 (2003)
Background Reference 03
Daniels, R.J., et al. Hum. Mol. Genet. 10 (4) :339-352 (2001)
Other Product Names
Probable crossover junction endonuclease EME2, 3122-, EME2
Tested Applications
WB
Physical Properties
Liquid
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