MOCS2 Antibody

Product Specifications

Background

Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.

NCBI Gene ID

4338

Swiss Prot

O96007

Accession Number

O96007

Host

Rabbit

Reactivity

Human

Immunogen

This MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human MOCS2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MOCS2

NCBI Official Name

Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}

NCBI Organism

Homo sapiens

Background Reference 01

Per, H., et al. Brain Dev. 29 (6) :365-368 (2007)

Background Reference 02

Hahnewald, R., et al. Mol. Genet. Metab. 89 (3) :210-213 (2006)

Background Reference 03

Beausoleil, S.A., et al. Nat. Biotechnol. 24 (10) :1285-1292 (2006)

Background Reference 04

Leimkuhler, S., et al. Hum. Genet. 117 (6) :565-570 (2005)

Other Product Names

Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}, 28112 {ECO:0000255|HAMAP-Rule:MF_03052}, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdenum cofactor synthesis protein 2B {ECO:0000255|HAMAP-Rule:MF_03052}, MOCS2B {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdopterin-synthase large subunit, MPT synthase large subunit, MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}, MCBPE, MOCO1