MRC2 Antibody

Product Specifications

Background

MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]) .[supplied by OMIM].

NCBI Gene ID

9902

Swiss Prot

Q9UBG0

Accession Number

Q9UBG0

Host

Rabbit

Reactivity

Human

Immunogen

This MRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the Central region of human MRC2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

167 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MRC2

NCBI Official Name

C-type mannose receptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Messaritou, G., et al. J. Cell. Sci. 122 (PT 22), 4042-4048 (2009) :

Background Reference 02

Wu, X., et al. Cancer Prev Res (Phila Pa) 2 (7) :617-624 (2009)

Background Reference 03

Wienke, D., et al. Cancer Res. 67 (21) :10230-10240 (2007)

Background Reference 04

Sulek, J., et al. J. Histochem. Cytochem. 55 (4) :347-353 (2007)

Other Product Names

C-type mannose receptor 2, C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, Urokinase receptor-associated protein, CD280, MRC2, CLEC13E, ENDO180, KIAA0709, UPARAP