CHRD Antibody
Product Specifications
Background
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
NCBI Gene ID
8646
Swiss Prot
Q9H2X0
Accession Number
Q9H2X0
Host
Rabbit
Reactivity
Mouse
Immunogen
This CHRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-467 amino acids from the Central region of human CHRD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CHRD
NCBI Official Name
Chordin
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)
Background Reference 03
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 04
Kwong, F.N., et al. J. Orthop. Res. 27 (6) :752-757 (2009)
Other Product Names
Chordin, CHRD
Tested Applications
WB
Protein ID
118572631
Physical Properties
Liquid
Curated Selection
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