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SPINT1 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.

NCBI Gene ID

6692

Swiss Prot

O43278

Accession Number

O43278

Host

Rabbit

Reactivity

Human

Immunogen

This SPINT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-207 amino acids from the Central region of human SPINT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SPINT1

NCBI Official Name

Kunitz-type protease inhibitor 1

NCBI Organism

Homo sapiens

Background Reference 01

Chen, Y.W., et al. J. Biol. Chem. 285 (41) :31755-31762 (2010)

Background Reference 02

Kauppinen, J.M., et al. Cancer Epidemiol. Biomarkers Prev. 19 (9) :2133-2142 (2010)

Background Reference 03

Nakamura, K., et al. Int. J. Oncol. 35 (2) :239-248 (2009)

Background Reference 04

Wang, J.K., et al. Am. J. Physiol., Cell Physiol. 297 (2), C459-C470 (2009) :

Other Product Names

Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1, SPINT1, HAI1

Tested Applications

WB

Physical Properties

Liquid

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