P2RX2 Antibody

Product Specifications

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

NCBI Gene ID

22953

Swiss Prot

Q9UBL9

Accession Number

Q9UBL9

Host

Rabbit

Reactivity

Human

Immunogen

This P2RX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human P2RX2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

P2RX2

NCBI Official Name

P2X purinoceptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Allsopp, R.C., et al. J. Biol. Chem. 285 (43) :32770-32777 (2010)

Background Reference 02

Decker, D.A., et al. Neurogastroenterol. Motil. 22 (8) :901-908 (2010)

Background Reference 03

Coddou, C., et al. J. Neurosci. 29 (39) :12284-12291 (2009)

Background Reference 04

Pannek, J., et al. Spinal Cord 47 (7) :561-564 (2009)

Other Product Names

P2X purinoceptor 2, P2X2, ATP receptor, Purinergic receptor, P2RX2, P2X2

Tested Applications

Protein ID

12643353

Physical Properties

Liquid

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