ATF5 Antibody

Product Specifications

Background

Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.

NCBI Gene ID

22809

Swiss Prot

Q9Y2D1

Accession Number

Q9Y2D1

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ATF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the C-terminal region of human ATF5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ATF5

NCBI Official Name

Cyclic AMP-dependent transcription factor ATF-5

NCBI Organism

Homo sapiens

Background Reference 01

Wei, Y., et al. J. Biochem. 148 (2) :171-178 (2010)

Background Reference 02

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 03

Tomppo, L., et al. Biol. Psychiatry 65 (12) :1055-1062 (2009)

Background Reference 04

Li, G., et al. Mol. Cancer Res. 7 (6) :933-943 (2009)

Other Product Names

Cyclic AMP-dependent transcription factor ATF-5, cAMP-dependent transcription factor ATF-5, Activating transcription factor 5, Transcription factor ATFx, ATF5, ATFX