Mouse Map4k2 Antibody

Product Specifications

Background

Enhances MAP3K1 oligomerization, which may relieve amino-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation. May play a role in the regulation of vesicle targeting or fusion.

NCBI Gene ID

26412

Swiss Prot

Q61161

Accession Number

Q61161

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Map4k2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 432-459 amino acids from the Central region of mouse Map4k2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

91 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Map4k2

NCBI Official Name

Mitogen-activated protein kinase kinase kinase kinase 2

NCBI Organism

Mus musculus

Background Reference 01

Zhong, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (11) :4372-4377 (2009)

Background Reference 02

Ren, M., et al. Proc. Natl. Acad. Sci. U.S.A. 93 (10) :5151-5155 (1996)

Other Product Names

Mitogen-activated protein kinase kinase kinase kinase 2, Germinal center kinase, GCK, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Rab8-interacting protein, Map4k2, Rab8ip