Mouse Acvr2a Antibody

Product Specifications

Background

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

NCBI Gene ID

11480

Swiss Prot

P27038

Accession Number

P27038

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Acvr2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of mouse Acvr2a.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Acvr2a

NCBI Official Name

Activin receptor type-2A

NCBI Organism

Mus musculus

Background Reference 01

Perron, J.C., et al. PLoS ONE (12), E8198 (2009) :

Background Reference 02

Morita, S., et al. PLoS ONE (1), E4212 (2009) :

Background Reference 03

Kamiya, N., et al. Development 135 (22) :3801-3811 (2008)

Background Reference 04

Xia, Y., et al. J. Biol. Chem. 282 (25) :18129-18140 (2007)

Other Product Names

Activin receptor type-2A, Activin receptor type IIA, ACTR-IIA, Acvr2a, Acvr2

Tested Applications

Physical Properties

Liquid

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