CD3G Antibody
Product Specifications
Background
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
NCBI Gene ID
917
Swiss Prot
P09693
Accession Number
P09693
Host
Rabbit
Reactivity
Human
Immunogen
This CD3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human CD3G.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
20 kDa
Fragment
Rabbit Ig
Symbol
CD3G
NCBI Official Name
T-cell surface glycoprotein CD3 gamma chain
NCBI Organism
Homo sapiens
Background Reference 01
Siegers, G.M., J. Exp. Med. 204 (11), 2537-2544 (2007)
Background Reference 02
Sigalov, A.B., Biochemistry 45 (51), 15731-15739 (2006)
Other Product Names
T-cell surface glycoprotein CD3 gamma chain, T-cell receptor T3 gamma chain, CD3g, CD3G, T3G
Tested Applications
WB, IHC-P, Flow
Protein ID
115993
Physical Properties
Liquid
Curated Selection
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