CD19 Antibody

Product Specifications

Background

Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

NCBI Gene ID

930

Swiss Prot

P15391

Accession Number

P15391

Host

Rabbit

Reactivity

Human

Immunogen

This CD19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393-421 amino acids from the C-terminal region of human CD19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CD19

NCBI Official Name

B-lymphocyte antigen CD19

NCBI Organism

Homo sapiens

Background Reference 01

Deaglio, S., Blood 109 (12), 5390-5398 (2007) Bradbury, L.E., J. Immunol. 149 (9), 2841-2850 (1992) Kozmik, Z., Mol. Cell. Biol. 12 (6), 2662-2672 (1992)