CALCA/CT Antibody

Product Specifications

Background

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

796

Swiss Prot

P01258

Accession Number

P01258

Host

Rabbit

Reactivity

Human

Immunogen

This CALCA/CT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the C-terminal region of human CALCA/CT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CALCA

NCBI Official Name

Calcitonin

NCBI Organism

Homo sapiens

Background Reference 01

Giroux, S., et al. Bone 47 (5) :975-981 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Lee, J.Y., et al. KoreanLab Med 30 (4) :406-413 (2010)

Background Reference 04

Giovanella, L., et al. Clin. Chem. Lab. Med. 48 (8) :1163-1165 (2010)

Other Product Names

Calcitonin, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1

Tested Applications

Protein ID

322510018

Physical Properties

Liquid

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