DVL2 Antibody

Product Specifications

Background

This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

NCBI Gene ID

1856

Swiss Prot

O14641

Accession Number

O14641

Host

Rabbit

Reactivity

Human

Immunogen

This DVL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the C-terminal region of human DVL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

79 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

DVL2

NCBI Official Name

Segment polarity protein dishevelled homolog DVL-2

NCBI Organism

Homo sapiens

Background Reference 01

Inkster, B., et al. Neuroimage 53 (3) :908-917 (2010)

Background Reference 02

Kikuchi, K., et al. EMBO J. 29 (20) :3470-3483 (2010)

Background Reference 03

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 04

Gao, C., et al. Nat. Cell Biol. 12 (8) :781-790 (2010)

Other Product Names

Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2

Tested Applications

Physical Properties

Liquid

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