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KRT7 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

NCBI Gene ID

3855

Swiss Prot

P08729

Accession Number

P08729

Host

Rabbit

Reactivity

Human

Immunogen

This KRT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human KRT7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

KRT7

NCBI Official Name

Keratin, type II cytoskeletal 7

NCBI Organism

Homo sapiens

Background Reference 01

Tsai, Y.Y., et al. Acta Derm. Venereol. 90 (4) :438-439 (2010)

Background Reference 02

Stewart, C.J., et al. Histopathology 57 (1) :46-54 (2010)

Background Reference 03

Nagashio, R., et al. Pathol. Int. 60 (2) :71-77 (2010)

Background Reference 04

Sano, M., et al. Int. J. Oncol. 36 (2) :321-330 (2010)

Other Product Names

Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL

Tested Applications

WB, IHC-P

Protein ID

317373583

Physical Properties

Liquid

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