ECT2 Antibody
Product Specifications
Background
The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis.
NCBI Gene ID
1894
Swiss Prot
Q9H8V3
Accession Number
Q9H8V3
Host
Rabbit
Reactivity
Human
Immunogen
This ECT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 597-625 amino acids from the Central region of human ECT2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
104 kDa
Fragment
Rabbit Ig
Symbol
ECT2
NCBI Official Name
Protein ECT2
NCBI Organism
Homo sapiens
Background Reference 01
Justilien, V., et al. Oncogene 28 (41) :3597-3607 (2009)
Background Reference 02
Burkard, M.E., et al. PLoS Biol. (5), E1000111 (2009) :
Background Reference 03
Wolfe, B.A., et al. PLoS Biol. (5), E1000110 (2009) :
Background Reference 04
Hirata, D., et al. Clin. Cancer Res. 15 (1) :256-266 (2009)
Other Product Names
Protein ECT2, Epithelial cell-transforming sequence 2 oncogene, ECT2
Tested Applications
WB, IHC-P
Protein ID
357529579
Physical Properties
Liquid
Curated Selection
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