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P2RY2 Antibody

Product Specifications

Background

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene.

NCBI Gene ID

5029

Swiss Prot

P41231

Accession Number

P41231

Host

Rabbit

Reactivity

Human

Immunogen

This P2RY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-352 amino acids from the C-terminal region of human P2RY2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

P2RY2

NCBI Official Name

P2Y purinoceptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Boucher, I., et al. Am. J. Physiol., Cell Physiol. 299 (2), C411-C421 (2010) :

Background Reference 03

Ratchford, A.M., et al. J. Biol. Chem. 285 (10) :7545-7555 (2010)

Background Reference 04

Taboubi, S., et al. Mol. Biol. Cell 21 (6) :946-955 (2010)

Other Product Names

P2Y purinoceptor 2, P2Y2, ATP receptor, P2U purinoceptor 1, P2U1, P2U receptor 1, Purinergic receptor, P2RY2, P2RU1

Tested Applications

WB

Protein ID

311033490

Physical Properties

Liquid

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