VAMP3 Antibody

Product Specifications

Background

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.

NCBI Gene ID

9341

Swiss Prot

Q15836

Accession Number

Q15836

Host

Rabbit

Reactivity

Human, Mouse, Zebrafish

Immunogen

This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat, Monkey

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Symbol

VAMP3

NCBI Official Name

Vesicle-associated membrane protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Ban, H.J., et al. BMC Genet. 11, 26 (2010) :

Background Reference 02

Fader, C.M., et al. Biochim. Biophys. Acta 1793 (12) :1901-1916 (2009)

Background Reference 03

Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :

Background Reference 04

Vassilopoulos, S., et al. Science 324 (5931) :1192-1196 (2009)

Other Product Names

Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3

Tested Applications

WB, IHC-P

Protein ID

2501082

Physical Properties

Liquid

Curated Selection

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