PDE8A Antibody
Product Specifications
Background
PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
NCBI Gene ID
5151
Swiss Prot
O60658
Accession Number
O60658
Host
Rabbit
Reactivity
Human
Immunogen
This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Symbol
PDE8A
NCBI Official Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
NCBI Organism
Homo sapiens
Background Reference 01
Wu, P., Proc. Natl. Acad. Sci. U.S.A. 101 (51), 17634-17639 (2004)
Background Reference 02
Gamanuma, M., Cell. Signal. 15 (6), 565-574 (2003)
Other Product Names
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Curated Selection
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