Mouse Prkcd Antibody

Product Specifications

Background

This is calcium-independent, phospholipid-dependent, serine-and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin (By similarity) .

NCBI Gene ID

18753

Swiss Prot

P28867

Accession Number

P28867

Host

Rabbit

Reactivity

Mouse

Immunogen

This Mouse Prkcd antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of mouse Prkcd.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

78 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Prkcd

NCBI Official Name

Protein kinase C delta type

NCBI Organism

Mus musculus

Background Reference 01

Ronda, A.C., et al. J. Steroid Biochem. Mol. Biol. 122 (4) :287-294 (2010)

Background Reference 02

Li, X., et al. J. Am. Soc. Nephrol. 21 (7) :1115-1124 (2010)

Background Reference 03

Romanova, L.Y., et al. J. Cell. Sci. 123 (PT 9), 1567-1577 (2010) :

Background Reference 04

White, M.C., et al. PLoS Genet. (6), E1000984 (2010) :

Other Product Names

Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta, Protein kinase C delta type regulatory subunit, Protein kinase C delta type catalytic subunit, Sphingosine-dependent protein kinase-1, SDK1, Prkcd, Pkcd