AIP Antibody

Product Specifications

Background

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

NCBI Gene ID

9049

Swiss Prot

O00170

Accession Number

O00170

Host

Rabbit

Reactivity

Human

Immunogen

This AIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-321 amino acids from the C-terminal region of human AIP.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

38 kDa

Fragment

Rabbit Ig

Symbol

AIP

NCBI Official Name

AH receptor-interacting protein

NCBI Organism

Homo sapiens

Background Reference 01

Daly, A.F., et al. J. Clin. Endocrinol. Metab. 95 (11), E373-E383 (2010) :

Background Reference 02

Stratakis, C.A., et al. Clin. Genet. 78 (5) :457-463 (2010)

Background Reference 03

Occhi, G., et al. Eur. J. Endocrinol. 163 (3) :369-376 (2010)

Background Reference 04

Igreja, S., et al. Hum. Mutat. 31 (8) :950-960 (2010)

Other Product Names

AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, AIP, XAP2