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FDFT1 Antibody

Product Specifications

Background

This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

NCBI Gene ID

2222

Swiss Prot

P37268

Accession Number

P37268

Host

Rabbit

Reactivity

Human

Immunogen

This FDFT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-361 amino acids from the C-terminal region of human FDFT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

FDFT1

NCBI Official Name

Squalene synthase

NCBI Organism

Homo sapiens

Background Reference 01

Chalasani, N., et al. Gastroenterology 139 (5) :1567-1576 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Kovanen, L., et al. Alcohol Alcohol. 45 (4) :303-311 (2010)

Background Reference 04

Lipkin, S.M., et al. Cancer Prev Res (Phila) 3 (5) :597-603 (2010)

Other Product Names

Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase, FDFT1

Tested Applications

WB

Protein ID

585126

Physical Properties

Liquid

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