STS Antibody

Product Specifications

Background

The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI) .

NCBI Gene ID

412

Swiss Prot

P08842

Accession Number

P08842

Host

Rabbit

Reactivity

Human

Immunogen

This STS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-517 amino acids from the C-terminal region of human STS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Symbol

STS

NCBI Official Name

Steryl-sulfatase

NCBI Organism

Homo sapiens

Background Reference 01

Chanplakorn, N., et al. Breast Cancer Res. Treat. 120 (3) :639-648 (2010)

Background Reference 02

Gruber, R., et al. J. Dermatol. Sci. 58 (1) :72-75 (2010)

Background Reference 03

Canueto, J., et al.Eur Acad Dermatol Venereol (2010) In press :

Background Reference 04

Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :

Other Product Names

Steryl-sulfatase, Arylsulfatase C, ASC, Steroid sulfatase, Steryl-sulfate sulfohydrolase, STS, ARSC1

Tested Applications

WB, IHC-P

Protein ID

135006

Physical Properties

Liquid

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