KLF1 Antibody
Product Specifications
Background
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype.
NCBI Gene ID
10661
Swiss Prot
Q13351
Accession Number
Q13351
Host
Rabbit
Reactivity
Human
Immunogen
This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human KLF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
38 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KLF1
NCBI Official Name
Krueppel-like factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Borg, J., et al. Nat. Genet. 42 (9) :801-805 (2010)
Background Reference 02
Zhou, D., et al. Nat. Genet. 42 (9) :742-744 (2010)
Background Reference 03
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 04
Papachatzopoulou, A., et al. Hemoglobin 34 (4) :333-342 (2010)
Other Product Names
Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF, KLF1, EKLF
Tested Applications
WB
Protein ID
2501699
Physical Properties
Liquid
Curated Selection
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