Mouse Taok2 Antibody

Product Specifications

Background

Taok2 may play a role in apoptotic morphological changes. May affect microtubule organization and stability. May play a role in the osmotic stress-MAPK8 pathway. Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases. Prevents MAP3K7-mediated activation of IKKA, and thus NF-kappa-B activation. Phosphorylates itself, MBP, activated MAPK8 and tubulins (By similarity) .

NCBI Gene ID

381921

Swiss Prot

Q6ZQ29

Accession Number

Q6ZQ29

Host

Rabbit

Reactivity

Human

Immunogen

This Mouse Taok2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of mouse Taok2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

139 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

Taok2

NCBI Official Name

Serine/threonine-protein kinase TAO2

NCBI Organism

Mus musculus

Background Reference 01

Blackshaw, S., et al. PLoS Biol. (9), E247 (2004) :

Background Reference 02

Thuret, S., et al. Mol. Cell. Neurosci. 25 (3) :394-405 (2004)

Background Reference 03

Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (24) :14109-14114 (2003)

Background Reference 04

Okazaki, N., et al. DNA Res. 10 (4) :167-180 (2003)

Other Product Names

Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, Taok2, Kiaa0881

Tested Applications

Physical Properties

Liquid

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