OTUB2 Antibody

Product Specifications

Background

Otubains are deubiquitylating cysteine proteases (DUBs; see MIM 602519) that belong to the ovarian tumor (OTU) protein superfamily. Like other DUBs, otubains cleave proteins precisely at the ubiquitin (UB; see MIM 191339) -protein bond.

NCBI Gene ID

78990

Swiss Prot

Q96DC9

Accession Number

Q96DC9

Host

Rabbit

Reactivity

Human

Immunogen

This OTUB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human OTUB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

OTUB2

NCBI Official Name

Ubiquitin thioesterase OTUB2

NCBI Organism

Homo sapiens

Background Reference 01

Li, S., et al. J. Biol. Chem. 285 (7) :4291-4297 (2010)

Background Reference 02

Sowa, M.E., et al. Cell 138 (2) :389-403 (2009)

Background Reference 03

Edelmann, M.J., et al. Biochem. J. 418 (2) :379-390 (2009)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Ubiquitin thioesterase OTUB2, Deubiquitinating enzyme OTUB2, OTU domain-containing ubiquitin aldehyde-binding protein 2, Otubain-2, Ubiquitin-specific-processing protease OTUB2, OTUB2, C14orf137, OTB2, OTU2