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Mouse Prkaca/Prkacb Antibody

Product Specifications

Background

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.

NCBI Gene ID

18749

Swiss Prot

P68181

Accession Number

P68181

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Mouse Prkaca/Prkacb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of mouse Prkaca/Prkacb.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

Prkacb

NCBI Official Name

CAMP-dependent protein kinase catalytic subunit beta

NCBI Organism

Mus musculus

Background Reference 01

Ribeiro, R.A., et al. Br. J. Nutr. 104 (8) :1148-1155 (2010)

Background Reference 02

Liu, J.X., et al. Seizure 19 (7) :414-420 (2010)

Background Reference 03

Ha, C.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15467-15472 (2010)

Background Reference 04

Sarma, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (29) :13165-13170 (2010)

Other Product Names

CAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, Prkacb, Pkacb

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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